Table 2. mRNA-Fold Gene Expression Differences on the Expression of Biomarkers in FLO-1 Cells Co-Cultured With C. concisus^a,b.

Biomarkers	Time, h				P Value
	1	3	5	7
p53					< 0.001
T	677 ± 3	417 ± 3.26	238 ± 2.2	201 ± 2
C	198 ± 2	166 ± 2.21	205 ± 1.2	182 ± 1
IL-18					< 0.05
T	804 ± 1.5	2053 ± 1.39	3566 ± 1.82	2009 ± 0.95
C	2924 ± 1.65	2649 ± 2.65	2840 ± 1.45	2521 ± 1.72
TNFα					< 0.001
T	30 ± 3	277 ± 2.16	433 ± 3.45	251 ± 3.23
C	53 ±3	64 ± 2.45	81 ± 3.2	65 ± 3.5

^aAbbreviations: T, test; C, control.

^bAll assays were performed in triplicate. Results are means ± SEM from three independent experiments compared with non-stimulated controls, analysed by two-way ANOVA followed by Bonferroni post-test analysis.