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. Author manuscript; available in PMC: 2017 Feb 15.
Published in final edited form as: J Immunol. 2016 Jan 15;196(4):1461–1470. doi: 10.4049/jimmunol.1501932

FIGURE 5.

FIGURE 5

Fluvastatin suppresses FcεRI signaling. (A) C57BL/6 BMMC were cultured in DMSO or fluvastatin as described in Figure 1, then subjected to western blotting to detect Syk, Lyn or Fyn. (B) BMMC from the indicated strains were cultured for 24 hours with IgE plus DMSO or fluvastatin (10μM) prior to antigen-mediated activation for 5 minutes, then analyzed by western blotting to detect the indicated total and phosphorylated proteins. Data are means ± SEM analyzed by unpaired t-Test of (A) 9 samples and (B) three independent experiments.