Skip to main content
. Author manuscript; available in PMC: 2017 Feb 15.
Published in final edited form as: J Immunol. 2016 Jan 15;196(4):1443–1448. doi: 10.4049/jimmunol.1501634

Figure 1. CD99 is required for lymphocyte TEM at the human BBB model in vitro.

Figure 1

TEM assays were performed with total lymphocytes (A) or purified CD4+ and CD8+ T-cells (C) on inflamed BBB model monolayers in the presence of anti-CD99 or control mAbs (non-blocking anti-VE-cadherin). (B,D) The number of lymphocytes that adhered to the monolayer were scored for multiple high power fields in each monolayer. Data represent the mean ± SD of hundreds of TEM events from at least six replicates from two (C,D) and three (A,B) independent experiments. **p< 0.001 (unpaired t-Test and two-way ANOVA).