Table 3.
Logistic regression model of ‘amplified HIV transmission risk’
| Characteristics | Level | Bivariate model | Multivariable modela | ||
|---|---|---|---|---|---|
| OR (95 % CI) | p | OR (95 % CI) | p | ||
| Site | Brazil vs. Thailand | 2.80 (1.84, 4.25) | <0.0001 | 2.44 (1.56, 3.83) | .0001 |
| Risk group | Heterosexual women vs. heterosexual men | 1.67 (0.94, 2.96) | .0782 | 1.50 (0.83, 2.74) | .1828 |
| MSM vs. heterosexual men | 3.26 (1.89, 5.63) | <0.0001 | 2.89 (1.65, 5.07) | .0002 | |
| Substance use | No vs. yes | 0.60 (0.34, 1.04) | .0702 | 0.86 (0.46, 1.60) | .6323 |
| CESD | Mild to moderate depression vs. no depression | 0.92 (0.55, 1.54) | .7586 | ||
| Severe depression vs. no depression | 1.42 (0.87, 2.32) | .1659 | |||
| ART adherence | Excellent vs. very poor | 0.59 (0.09, 3.84) | .5841 | ||
| Very good vs. very poor | 0.35 (0.06, 2.23) | .2688 | |||
| Good vs. very poor | 0.50 (0.08, 3.14) | .4636 | |||
| Fair vs. very poor | 0.75 (0.11, 4.92) | .7644 | |||
| Poor vs. very poor | 1.50 (0.14, 16.54) | .7406 | |||
| ACTG SF-21 scales | |||||
| General health | General health | 1.00 (0.99, 1.01) | .5030 | ||
| Physical functioning | Physical functioning | 0.99 (0.98, 1.00) | .1320 | ||
| Role functioning | Role functioning | 0.99 (0.99, 1.00) | .2321 | ||
| Social functioning | Social functioning | 1.00 (0.99, 1.01) | .6076 | ||
| Cognitive functioning | Cognitive functioning | 0.99 (0.98, 1.00) | .1504 | ||
| Pain | Pain | 1.00 (0.99, 1.01) | .9297 | ||
| Mental health | Mental health | 1.00 (0.98, 1.01) | .5761 | ||
| Energy/fatigue | Energy/fatigue | 1.00 (0.99, 1.01) | .4415 | ||
| Social support | Social support | 0.99 (0.95, 1.02) | .3948 | ||
| HIV disclosure | Factor 1 (disclosure) | 0.77 (0.47, 1.25) | .2874 | ||
| Factor 2 (fear of consequences of disclosure) | 1.81 (1.22, 2.67) | .0029 | 1.39 (0.92, 2.08) | .1159 | |
| Alcohol score | AUDIT score | 1.01 (0.98, 1.04) | .5319 | ||
Amplified HIV transmission risk was defined as detectable viral load OR STI and engaged in condomless anal or vaginal sex with an HIV-uninfected or unknown status partner in past three months. Not being in this amplified HIV transmission risk category was defined as suppressed viral load and no STI or no condomless insertive or penetrative sex with an HIV-uninfected or unknown status partner in the past 3 months. This analysis only includes individuals where HIV RNA data were available (from Thailand and Brazil) and STI lab test results (n = 457)
a
Covariates with p < .1 were included in the multivariable model