Figure 3.

Mean individual predicted efavirenz concentrations at 12 hours postdose (C₁₂) on a log scale stratified for metabolizer status (extensive, intermediate, slow) and dose (400 and 600 mg once daily; n = 295 and n = 273, respectively). The black dashed line illustrates the recommended minimum effective concentration for efavirenz (MEC) of 1.0 mg/L. Each point represents an individual patient and the solid black line the median concentrations. Numbers of patients with C₁₂ below the MEC or with detectable or missing viral load at 48 weeks are shown. C₁₂: concentration 12 hours post‐dose representing the mid‐dose interval concentration; VL: viral load.