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. 2015 Jul 24;70(10):1269–1277. doi: 10.1111/all.12679

Figure 2.

Figure 2

The starting frequency of eGC and memory B cells is predictive of CSR to IgE. Surface staining of CD27 and CD38 on purified tonsil B cells was used to assess the proportions of naïve, eGC, GC, and memory B cells and plasmablasts at the outset of culture. Representative FACS plots from low‐ and high‐switched cultures are shown in (A), and the data showing the mean (±SD) from low‐switched (n = 8) and high‐switched (n = 7) cell cultures are summarized in (B). (C) Correlation of day 12 IgE+ cell percentages with day 0 memory and eGC B‐cell percentages. Correlation analysis was performed using Spearman's rank correlation coefficient (***P < 0.001).