Table 3.
Hepatic Copper Levels in Various Phenotypes and Age Groups of WD Patients
| Groups | No. | Hepatic Copper Level (μg/g dry wt) Mean ± SD 95% CI Range | P Value |
|---|---|---|---|
| Phenotype | |||
| Pure liver disease, H | 105 | 915.4 ± 365.3 844.7‐986.1 337.0‐1,968.0 | 0.006 |
| Liver and neurological disease, N1 | 25 | 702. 3 ± 389.3 541.6‐863.0 118.0‐1,540.0 | |
| Pure neurological, N2 | 31 | 411.3 ± 262.9 313.3‐509.5 210.0‐1,363.0 | 0.001 |
| Presymptomatic, P | 17 | 737.8 ± 245.0 607.2‐868.4 357.0‐1,149.0 | |
| Age group, years old | |||
| 0‐7 | 16 | 1,113.3 ± 289.8 958.9‐1,267.7 639.0‐1,650.0 | 0.001 |
| 8‐14 | 55 | 927.0 ± 403.8 817.8‐1,036.1 118.0‐1,968.0 | 0.001 |
| 15‐21 | 47 | 626.3 ± 338.1 527.0‐725.6 212.0‐1,732.0 | |
| 22‐27 | 26 | 661.0 ± 354.0 518.0‐804.0 213.0‐1,540.0 | |
| 28‐35 | 13 | 745.8 ± 281.5 475.7‐915.9 445.0‐1,356.7 | |
| ≥36 | 21 | 639.4 ± 366.6 472.5‐806.2 233.0‐1,504.0 |
Abbreviation: CI, confidence interval.