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. 2015 Jun 16;107(7):232–244. doi: 10.1111/boc.201400097

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© 2015 The Authors. Biology of the Cell published by John Wiley & Sons Ltd on behalf of Société Française des Microscopies and Société de Biologie Cellulaire de France.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Metastatic fingerprint (n = 654) discovered from the Mayo Clinic I showing that most of the features are up‐regulated in the metastatic group

(A) Heatmap showing three main correlated groups of upregulated genes, among which is the SChLAP1 region. (B) Approximately half of the features are non‐coding (lncRNA, intronic, intergenic and anti‐sense). (C) SChLAP1 and UBE2C are the top upregulated lncRNA and coding RNA respectively in the metastatic group, and MYBPC1 is the most down‐regulated. (D) The metastatic fingerprint is representing the biology of metastasis tissues from MSKCC. Most of features up‐regulated in localised cancer with metastatic outcome (Prim‐Met) are also up‐regulated in metastasis lesions.