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. 2016 Jan 19;96(6):414–426. doi: 10.1111/iep.12161

Table 1.

The Scoring System used for pathological interpretation

Numerical value Symbol Histopathological description Immunohistochemistry description
1 + Small focal microgranuloma composed mainly of macrophages, lymphocytes and plasma cells Very few (<5) stained cells
2 ++ Non‐necrotic multifocal solid lesions Small number (5 – 20) stained cells
3 +++ Focal or multifocal suppurative lesions with the presence of abundant neutrophils and small areas of necrosis Moderate number (20–50) stained cells
4 ++++ Multifocal lesion with severe necrosis Abundant (>50) stained cells