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. 2016 Feb 8;10:8. doi: 10.3389/fncom.2016.00008

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Copyright © 2016 Horne, Sumner and Seeber.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The dependence of threshold on phase duration under cathodic-anodic biphasic stimulation. (A) The effect on threshold of increasing the anodic-phase duration in the BLIF neuron (solid line) and an ANF (Miller et al., 2001; open circles). The stimulus is an asymmetric, cathodic-anodic biphasic pulse (40 μs leading-phase duration) of varying anodic-phase duration. The amplitude of the anodic phase is adjusted to maintain charge balance. (B) Strength-duration functions of the BLIF neuron (solid line) and a cat ANF (Shepherd et al., 2001; open circles) when stimulated with a symmetric, cathodic-anodic biphasic stimulus (0 μs IPG).