Figure 3.

CSF pTau₁₈₁ level and functional connectivity during DMN. (A) CSF pTau₁₈₁ during rest and task at various significant p-values; the significant p-values (y-axis) of the correlation between pTau₁₈₁ and connectivity of brain regions were found only during task, but not during resting state; (B) pTau₁₈₁ and bilateral inferior parietal connectivity during task. Individuals with stronger lAG–rAG have higher level of pTau₁₈₁, which indicates higher risk of tau-related neural degeneration.