FIG. 6.

Sequence of genes expressed at the single-cell level by differentiating adult hMSCs. Schematic representation of the genes expressed (and monitored) during adult hMSC differentiation into the adipogenic, chondrogenic, and osteogenic lineages. SOX9, SRY (sex determining region Y)-box 9; ACAN, aggrecan; PPARG, peroxisome proliferator-activated receptor gamma; FAB4, fatty acid-binding protein 4; RHOA, ras homolog family member A; PROM1, prominin 1; NANOG, Nanog homeobox; TAZ, WW domain-containing transcription regulator 1; MSX2, msh homeobox 2; WNTs, a group of extracellular signaling molecules; FGFs, fibroblast growth factors; TGFB, transforming growth factor-beta; BMPs, bone morphogenetic proteins; IGFs, insulin-like growth factors.