Table 3.

Brain Regions Showing Reduced Functional Connectivity (Data-Based Approach) in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Subjects

RSN–brain region	x	y	z	k	t
SN—left posterior cingulate cortex	−3	−28	26	32	4.14
SMN—left anterior midcingulate cortex	−6	26	35	42	4.26
Left FPN—left superior frontal gyrus	−27	50	26	25	4.67

Threshold t-statistic of 4.0 and a cluster size (k) of 60 mm³.

x, y, and z coordinates are in MNI space.

FPN, frontoparietal network; RSN, resting-state network; SMN, sensory motor network; SN, salience network.