IgG magnitude and the effect of current blood-stage P. vivax infections. IgG responses to P. vivax (A) CSP247, (B) CSP210, and (C) CelTOS at visit 1. Volunteers are stratified into those uninfected throughout the cohort (group 1), those exposed but currently uninfected (group 2), and those exposed but currently infected (group 3). The dashed lines represent protein-specific positivity cutoffs. Statistical differences between the three groups were assessed using the Kruskal-Wallis test with Dunn's multiple-comparison test. *, P < 0.05.