TABLE 5.
Diagnostic capacity 8 weeks after M. bovis challenge (M. bovis PPD minus M. avium PPD)
| Treatment group | IL-17Aa |
IFN-γ |
||||||
|---|---|---|---|---|---|---|---|---|
| CSLb |
Lelystadb |
CSL |
Lelystad |
|||||
| ΔOD (mean ± SEM) |
No. positive | ΔOD (mean ± SEM) | No. positive | ΔOD (mean ± SEM) | No. positive | ΔOD (mean ± SEM) | No. positive | |
| No infection (n = 7) | 0.1 ± 0.04 | 2 | −0.1 ± 0.11 | 0 | 0.07 ± 0.01 | 1 | −0.1 ± 0.07 | 0 |
| M. bovis 95-1315 infection (n = 8) | 0.6 ± 0.07c | 8 | 0.7 ± 0.12c | 8 | 1.0 ± 0.12c | 7 | 1.7 ± 0.20c | 8 |
| M. bovis 10-7428 infection (n = 8) | 0.6 ± 0.15c | 8 | 0.7 ± 0.17c | 8 | 0.7 ± 0.30c | 8 | 1.4 ± 0.30c | 8 |
a
Data are presented as mean ± SEM of changes in optical densities (ODs) (i.e., M. bovis PPD minus M. avium PPD) and number positive (i.e., change in optical density of >0.1).
b
Sources of PPD.
c
Differs from the response by the noninfected group (P < 0.05, ANOVA followed by Tukey's multiple-comparison test).