Cell-mediated immune responses of cattle vaccinated with Adt vectors and challenged with FMDV O1 Campos. Flow cytometric data corresponding to the numbers of IFN-γ-producing CD4+ and CD8+ lymphocytes on vaccination day (A), 1 week postvaccination (B), 2 weeks postvaccination (C), on the day of challenge (D), 2 weeks postchallenge (E), and 3 weeks postchallenge (F). Error bars represent standard deviation of the mean. Statistical significance was determined with Student's t test. *, P < 0.05; **, P < 0.01.