Table 3. The relationship between the plasma level of HIF-1α and the clinical features.

	Cases	the plasma level of HIF-1α(pg/ml)	P
		Median(Range)
Age
≤60y	56	286.43(242.34–857.89)	0.268
>60y	44	322.06(153.04–754.30)
Gender
Male	80	297.70(153.04–857.89)	0.670
Female	20	288.14(243.62–754.30)
Pathological type
Adenocarcinoma	40	305.27(153.04–754.30)	0.573
Squamous cell carcinomas	50	286.02(219.84–857.89)
Others	10	272.09(242.34–635.60)
Tumor differentiation grade
Poorly differentiated	44	302.25(242.34–754.30)	0.397
Middle-, high-differentiated	56	286.43(153.04–857.89)
T stage
T1	30	320.55(257.46–754.30)	0.495
T2	59	286.94(153.04–857.89)
T3-4	11	307.70(250.81–558.71)
N stage
N0	64	285.51(153.04–797.68)	0.462
N1-2	36	330.74(242.34–857.89)
pTNM stage
I	43	285.92(153.04–797.68)	0.467
II	27	287.68(250.81–731.88)
III	31	335.92(242.34–857.89)
Diameter of tumor
≤4cm	59	302.77(153.04–857.89)	0.516
>4cm	42	285.92(219.84–757.68)
Smoking
Yes	59	302.76(219.84–857.89)	0.343
No	41	285.92(153.04–754.30)