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. 2015 Jul 3;78(3):426–438. doi: 10.1002/ana.24453

Figure 7.

Figure 7

Immunostaining for TDP‐43 and ubiquitin in several brain regions of 18‐month‐old mice. (A–C, G–I) Immunofluorescent staining of adult spinal cord using anti–TDP‐43 antibodies is shown. Nuclear TDP‐43 staining is detected in Nestin‐Cre+/−; C9orf72fl/fl mice and control littermates. (D–F, J–L) Representative images show immunostaining for ubiquitin in adult spinal cord. Ubiquitin expression is not affected by loss of C9orf72. DAPI = 4′,6‐diamidino‐2‐phenylindole; GCL = granule cell layer; H = hilus. Scale bars = 60μm.