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. 2016 Jan 6;24(2):283–290. doi: 10.1002/oby.21376

Figure 1.

Figure 1

A model for development of functional BAs in WAT. Thermogenic capacity determined by the number of adipocytes capable of activating the BAP in WAT is distinct among different strains of mice. The BAP in WAT is induced at 21 days of age and is transiently greater in mice reared at 17°C. The BAP disappears post‐weaning. Induction of the BAP in adult life is dependent on activation of the sympathetic nervous system, e.g., by cold exposure independently of environmental temperature during the lactation period.