Table 1.
Anatomical and molecular characterization of murine and human classical and BAs dispersed within WAT
| Mice | Humans | ||||
|---|---|---|---|---|---|
| Cellular origin | Anatomical distribution | Molecular biomarkers | Anatomical distribution | Molecular biomarkers | |
| Classical BAs |
En1+, Pax7+
Myf5+, Pax3+ |
Interscapular |
Zic1
18
Zic1, miR‐206, Lhx8 17, 39 Zic1, Lhx8, Epstl1 17, 39, 62 Eva1, Pdk4 40, 62 |
Interscapular Deep neck |
ZIC1
19
ZIC1, LHX8 23 |
| BAs dispersed in WAT | Myf5 ‐, Pdfrα+rWAT: Myf5+, Pax3+ |
Subcutaneous WAT Visceral WAT |
Hoxc9
18
Hoxc9, Shox2 17, 39 Fgf21, Car4, Cited1 62 Cd40, Tbx1, Cd137, Tmem26, Slc27a1 40 |
Supraclavicular Periadrenal |
Supraclavicular: miR‐206, miR‐133b, LHXB8, ZIC1, TBX1, TMEM26 74 MTUS1, KCNK3 73 TMEM26, SHOX2, TBX1 19 Periadrenal: HOXC9, EVA1, ZIC1 19 |