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. 2016 Jan 20;22(1):4–27. doi: 10.1002/psc.2836

Scheme 9.

Scheme 9

Use of diaminobenzoic acid linker (Dbz) as safety‐catch linker for peptide thioester Fmoc SPPS. (i) SPPS; (ii) 4‐nitrochloroformate; (iii) DIPEA; (iv) standard TFA cleavage; (v) R‐SH, NaSPh; (vi) 6 M guanidine, phosphate buffer pH 7.8, 1% thiophenol.