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. 2016 Feb 8;14:42. doi: 10.1186/s12967-016-0786-z

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© Sun et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Silenced TUG1 inhibited metastasis of CRC cells. a Representative image and number statistics for colony formation in LOVO^si-control and LOVO^si-TUG1 cells. b Wound-healing assay for motility of LOVO^si-control and LOVO^si-TUG1 cells. Representative pictures of one field at the beginning (t = 0) (left panel) and at the end (t = 12 h) (right panel) of the recording in each condition are shown. c Representative images of transwell migrated cells, and d invaded cells in stably transfected LOVO^si-control and LOVO^si-TUG1 cells and the average number of migrated cells and invaded cells are shown in the right of (c) and (d). Values represent mean ± SD. * P < 0.05 compared with si-control