Table 3.
ROS (% of basal) | Cytotoxicity (IC50, μM) | |
---|---|---|
Control | ||
H2O2 | 630 | 39 |
DMNQ | 695 | 37 |
| ||
+ Quercetin | ||
H2O2 | 130∗ | 157∗ |
DMNQ | 115∗ | 131∗ |
For ROS measurements, control or quercetin-pretreated cells (24 h, 20 μM) were exposed to either oxidant for 30 min. For cytotoxicity (assessed by the MTT assay) control or quercetin pretreated cells were exposed for 24 h to 4-5 concentrations of oxidants. ∗Significantly different from control, p < 0.01. Adapted from [34].