Table 2.
Effect of DLD (25 mg/kg/day) and DHD (50 mg/kg/day) on GSH, catalase, and SOD in DOX (15 mg/kg) induced nephrotoxicity.
| Group | GSH (mmol/g tissue) | Catalase (unit/g tissue) | SOD (unit/g tissue) |
|---|---|---|---|
| Control | 10.32 ± 0.2999 | 92.10 ± 2.835 | 829.7 ± 5.182 |
| DLD | 10.22 ± 0.5530 | 91.53 ± 1.860 | 832.0 ± 6.915 |
| DHD | 9.085 ± 0.3000 | 91.80 ± 2.127 | 826.6 ± 7.575 |
| DOX | 4.814 ± 0.1630a | 72.49 ± 3.662a | 657.6 ± 15.28a |
| DOX/DLD | 8.678 ± 0.1985ab | 80.48 ± 4.108 | 722.7 ± 41.13a |
| DOX/DHD | 9.215 ± 0.2814b | 8627 ± 4.496b | 807.3 ± 16.96b |
Values are representation of 4–6 observations as means ± SEM. Results are considered significantly different when P < 0.05. aSignificant difference compared to control; bsignificant difference compared to DOX group.