Table 4.
Association of serum vitamin D with OSDI score, corneal dendritic cell density, and corneal subbasal nerve plexus features in EDE patients.
| Serum vitamin D level | ||
|---|---|---|
| r | P value | |
| OSDI score | ||
| OSDI—total | −0.332 | 0.0095 |
| OSDI—discomfort | −0.375 | 0.0032 |
| OSDI—vision | −0.289 | 0.025 |
| Dendritic cells | ||
| Total cells (cells/mm2) | −0.184 | 0.1589 |
| DCs with dendrites (cells/mm2) | −0.322 | 0.0122 |
| DCs without dendrites (cells/mm2) | −0.099 | 0.45 |
| Subbasal nerve plexus | ||
| CNFL (length in mm/mm2) | −0.004 | 0.9749 |
| CNFD (major nerves/mm2) | 0.037 | 0.777 |
| CNFW (average nerve fiber width/mm2) | −0.083 | 0.5267 |
| CTBD (branch points/mm2) | −0.094 | 0.4742 |
| CNBD (number of branches/mm2) | −0.007 | 0.96 |
| CNFA (total nerve fiber area/mm2) | −0.011 | 0.9334 |
OSDI: ocular surface disease index; DCs: dendritic cells; CNFL: corneal nerve fiber length; CNFD: corneal nerve fiber density; CNFW: corneal nerve fiber width; CTBD: corneal total branch density; CNBD: corneal nerve branch density; CNFA: corneal nerve fiber area; r – Spearman correlation coefficient.