Table 2.
Name | Molecular target | Phase | Status | Patients | Weeks | Efficacy | Reference |
---|---|---|---|---|---|---|---|
Secukinumab | IL-17A | I | Completed | 52 | 6 | Supported | [70] |
II | Completed | 237 | 16 | Supported | [71] | ||
II | Completed | 174 | 52 | Supported | [72] | ||
III | Ongoing | n/a | n/a | n/a | NCT01377012 | ||
III | Ongoing | n/a | n/a | n/a | NCT01350804 | ||
| |||||||
Ixekizumab | IL-17A | I | Completed | 97 | 10 | Supported | [73] |
II | Completed | 448 | 12 | Supported | [74] | ||
| |||||||
Brodalumab | IL-17RA | I | Completed | 40 | 48 | Not confirmed | [75] |
II | Completed | 252 | 12 | Not confirmed | [76] |
n/a: no information available.