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. 2016 Jan 21;2016:8404092. doi: 10.1155/2016/8404092

Table 2.

A comparison between existing methods and the proposed method in this paper.

Instrumental method Extraction Clean-up MDL Reference
HPLC-UV Aqueous methanol Anionic SPE 30 [6]
CE-UV Aqueous methanol Anionic and cationic SPE 150 [8]
HPLC-FLD Aqueous methanol Anionic SPE 6 [9]
HPLC-UV Aqueous methanol Anion SPE 200 [13]
HPLC-MS Aqueous methanol Anion SPE 400 [13]
HPLC-MS/MS Methanol/acetone (Extraction with PLE) 200 [11]
HPLC-UV-MS/MS Aqueous methanol Online SPE 0.3 [15]
HPLC-MS/MS Aqueous methanol 63 [10]
HPLC-MS/MS Methanol 9 This paper

HPLC: high performance liquid chromatography; UV: ultraviolet detection; CE: capillary electrophoresis; FLD: fluorimetric detection; MS: mass spectrometry; MS/MS: tandem mass spectrometry; SPE: solid phase extraction; PLE: pressure liquid extraction.