Figure 2. High SERPINE1 expression is associated with poor outcome in patients with head and neck carcinoma in a prospective study.

A. Differences in SERPINE1 mRNA expression between normal mucosa and the evaluated tumor samples. Differences in local recurrence-free (LRFS) B. progression-free (PFS) C. and cancer-specific survival (CSS) D. according to SERPINE1 mRNA expression (n = 190). Differences in progression-free (PFS) E–F. and cancer-specific (CSS) G–H. survival according to SERPINE1 immunostaining in 69 patients included in the prospective cohort.