Skip to main content
. 2015 Aug 6;6(30):29129–29142. doi: 10.18632/oncotarget.4895

Figure 3. TRAF6 expression correlates with glioma grades, miR-146b-5p expression and patients’ prognoses.

Figure 3

A. Representative images of TRAF6 IHC detection. Scale bar, 50 μm. B. Comparisons among groups of TRAF6 expression level [Labeling index, LI (%)] in the FFPE samples of 147 gliomas and 20 nontumoral control brain tissues. The TRAF6 LI (%) of each sample was calculated according to percentage ratio of positive cell number to total cell number in 10 randomly selected microscopic fields at × 400, and the data in B are presented as the mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001. C and D. Pearson correlation analysis between TRAF6 and miR-146b-5p expressions in our FFPE samples (C) and the data from TCGA database (D) E–H. Kaplan-Meier analysis of the correlation between TRAF6 and DFS or and OS of all grade glioma patients (E and F) and glioblastoma patients (G and H). Patients were stratified into high and low expression subgroups using the median of TRAF6 LIs.