Figure 2. Relative activity of reporter gene constructed with wild type of 3′UTR of SLC30A1 a. SERPINB2 b. or AKR1C1 c. gene or their mutant types d. cotransfected with miR-182 or mir-185 or their inhibitors in A549 and H446 cells. Results are mean ± SEM obtained from three experiments and each had six replicates. *, P < 0.05 and **, P < 0.01 compared with without microRNA control or wild type. Mutations in the core microRNA binding sites are shown e.
