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. 2015 Jul 21;6(30):29585–29598. doi: 10.18632/oncotarget.4987

Figure 6. Integrin α7 was involved in S100P-mediated cancer progression.

Figure 6

A. The interaction of S100P with integrin α7. B. The efficacy of integrin α7 siRNA transfection. C. Knockdown of integrin α7 decreased S100P-mediated cell migration. D. Inhibition of integrin α7 reduced N-cadherin upregulation and FAK in S100P overexpressing CL1-0 cells. E. The expression of integrin α7 in CL1-0 and CL1-5 cells. Levels of integrin α7 were determined using anti-integrin α7 antibody. The cells were submitted to migration (transwell assay) and immunoblot. The expressions of various proteins were assessed by immunoblot. Data were shown as mean±SD. *p < 0.05 or significant difference between control and test groups.