Table 2. The list of highly up-regulated and down-regulated genes with a neuronal function detected in human control adipose tissue (AT) and AT-T2D using mRNA expression.

Protein ID	Protein description	pI	Mw (Da)	Gene name	AT-T2D vs AT-CONT (fold change)
Q9H2B2	Synaptotagmin-4	8.72	47,958	SYT4	362.08
Q9Y2G1	Myelin regulatory factor	7.05	124,397	C11ORF9/MYRF	95.06
Q9NQC3	Reticulon-4	4.42	129,931	RTN4	49.36
P18509	Pituitary adenylate cyclase-activating	9.83	18,835	ADCYAP1	48.92
P21246	Pleiotrophin	9.66	18,942	PTN	46.90
P37088	Amiloride-sensitive sodium channel alpha	7.47	75,704	SCNN1A	46.59
Q8WUT4	Leucine-rich repeat neuronal protein 4	6.82	78,843	C20ORF75/LRNN4	42.98
Q9P2J2	Protein turtle homolog A	6.74	126,58	IGSF9	35.06
O15240	Neurosecretory protein	4.76	67,258	VGF	−119.29
P24530	Endothelin B receptor	9.15	49,644	EDNRB	−41.21
P47928	DNA-binding protein inhibitor ID-4	8.69	16,622	ID4	−38.44
Q9UBY5	Lysophosphatidic acid receptor 3	9.53	40,128	LPAR3	−35.62
O14531	Dihydropyrimidinase-related protein 4	6.64	61,878	DPYSL4	−35.47
Q7Z5W6	lamininA 1	7.02	60,711	LAMA1	−34.41
Q9UIU6	Homeobox protein SIX4	5.45	82,933	SIX4	−34.09

Protein accession number, protein description, pI (isoelectric point), the Molecular weight (Mw), gene name of that protein, and fold change (AT-T2D vs AT-Control) are presented for each gene in this Table. The Mw expressed in Da. pI resulted from whole amino acid sequence of each protein and is derived from www.expasy.org.