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A. CAF-64 cells were treated with DMSO or challenged with curcumin (40 μM) for 24 h, and then total RNA was purified and the levels of the indicated RNAs were assessed by qRT-PCR. Error bars represent means ± S.D. *p value < 0.0081. B. Schematic representation of the role of miR-146b-5p in p16-dependent negative regulation of IL-6 and the consequent repression of breast stromal fibroblasts, and the effect of curcumin. See text for details.
