Table 2. Univariate Cox analysis.

Variable	Univariate analysis Recurrence		Univariate analysis OS		Univariate analysis DFS
	Hazard Ratio (95% CI)	P value	Hazard Ratio (95% CI)	P value	Hazard Ratio (95% CI)	P value
Age(<55 years vs ≥55 years)	1.06(0.62–1.82)	0.818	1.2(0.69–2.08)	0.526	1.21(0.73–2)	0.466
Gender(male vs female)	1.16(0.66–2.04)	0.615	1.03(0.57–1.85)	0.933	1.13(0.66–1.93)	0.649
Edmondson grade (I,II vs III,IV)	1.94(1.14–3.32)	0.015	2.12(1.22–3.69)	0.008	1.81(1.09–3)	0.021
HBV(absent vs present)	1.1(0.59–2.06)	0.768	1.2(0.63–2.3)	0.579	1.06(0.59–1.91)	0.834
HCV(absent vs present)	0.96(0.38–2.42)	0.935	1.27(0.54–2.99)	0.584	1.25(0.57–2.76)	0.58
AFP level(< 100 ng/ml vs ≥ 100 ng/ml)	1.73(0.97–3.09)	0.063	2.43(1.29–4.6)	0.006	1.81(1.05–3.13)	0.034
Liver cirrhosis (absent vs present)	0.89(0.51–1.59)	0.703	1.78(1.02–3.13)	0.043	1.24(0.74–2.08)	0.412
Tumor size (≤ 5 cm vs > 5 cm)	2.62(1.49–4.61)	0.001	2.25(1.27–3.98)	0.006	2.1(1.25–3.52)	0.005
Tumor stage (I,II vs III,IV)	3.23(1.87–5.57)	< 0.001	3.51(1.99–6.18)	< 0.001	2.71(1.61–4.58)	< 0.001
Vascular Invasion (absent vs present)	3.84(2.01–7.34)	< 0.001	4.46(2.21–9.01)	< 0.001	3.22(1.8–5.74)	< 0.001
Tumor number (Single vs Multi)	2.95(1.71–5.08)	< 0.001	3.98(2.26–7.02)	< 0.001	3.03(1.81–5.06)	< 0.001
VRK1(0,1 vs 2,3)	2.31(1.03–5.15)	0.041	2.06(0.92–4.62)	0.08	2.14(0.96–4.75)	0.062

* Data in which p < 0.05 are highlighted in bold.