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. 2015 Aug 17;6(30):30165–30177. doi: 10.18632/oncotarget.5030

Figure 2. Function of RASSF8 in melanoma.

Figure 2

A. Overexpression of RASSF8 inhibited cell growth in Wm266-4 (N = 3). B. Knockdown of RASSF8 expression promoted cell growth in M24 (N = 3). C. Overexpression of RASSF8 inhibits cell migration in Wn266-4 whereas knockdown of RASSF8 increases cell migration in M24 (N = 3). D. Overexpression of RASSF8 inhibits cell invasion in Wn266-4 whereas knockdown of RASSF8 increases cell invasion in M24 (N = 3). E. Overexpression of RASSF8 inhibits colony formation of melanoma cells in soft agar (N = 3) whereas knockdown of RASSF8 increases colony formation of melanoma cells in soft agar (N = 3). RASSF8 plays inhibitory role in growth and mobility of melanoma cells.