Table 1. Clinical/biological characteristics at diagnosis.

	n. 244
Età Median (range) yrs Età ≥ 55	59 (18–84) 147
Sex: M/F	173/71
WBCx109/L: mean ± 2SD WBC ≥ 30 × 109/L	13.9 ± 42.5 98 (40%)
Type of leukemia : De novo           Secondary	173 (71%) 71 (29%)
FAB (de novo): M0          M1          M2          M4          M5          M6	10 (6%) 32 (18%) 28 (16%) 35 (20%) 65 (38%) 3 (2%)
Combined cytogenetic/molecular risk: Favorable Int-1 Int-2 Unfavorable NA	43 (18%) 61 (25%) 35 (14%) 70 (29%) 35 (14%)
Flt3-ITD: mutated      wild type      NA	46 (19%) 170 (70%) 28 (11%)
NPM: mutated    wild type    NA	65 (27%) 145 (59%) 34 (14%)
Cytogenetic risk: Favorable Intermediate Unfavorable NA	14 (6%) 136 (56%) 70 (29%) 24 (10%)
CD34: positive     negative	130 (53%) 114 /47%)
CD56: positive     Negative     NA	87 (36%) 154 (63%) 3 (1%)
Bcl2-MFI: ≥ 17       <17       NA	124 (51%) 113 (46%) 7 (3%)