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. 2016 Feb 4;10:585–592. doi: 10.2147/DDDT.S96730

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© 2016 Xu et al. This work is published and licensed by Dove Medical Press Limited

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Construction of the rdHSV-IFNγ therapeutic system.

Notes: (A) HSV backbone of the recombined HSV-1. (B) Shuttle plasmids carrying the IFNγ gene. (C) The complete rdHSV-1-IFNγ therapeutic system.

Abbreviations: HSV-1, herpes simplex virus type 1; IFNγ, interferon gamma; rdHSV, replication-defective HSV-1; EF-1α, elongation factor 1 alpha; CMV, cytomegalovirus promoter.