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. 2016 Feb 2;11:515–527. doi: 10.2147/IJN.S98080

Figure 2.

Figure 2

Estimated response surfaces along with contour plots for the effect of the studied factors on the particle size (A and B) and solubility enhancement (C and D).

Abbreviations: X1, stabilizer concentration; X2, miscible solvent ratio; X3, homogenization speed; X4, homogenization time.