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Comparison of the effects of allopurinol and dobutamine on myocardial efficiency in dogs with pacing-induced heart failure. Compared with baseline, allopurinol significantly improves efficiency whereas dobutamines significantly decreases it. Solid symbols represent mean±SEM. *p < 0.05 vs dobutamine. (SW, stroke work; MVO2, myocardial oxygen consumption per unit time). Reproduced with permission from (38). Copyright 1999, American Heart Association.
