Table 1. Clinical summary.
Animal | Age | Sex | Baseline Weight | Time to lesion Development | Time to 10% Weight loss | Symptoms and signs | Euthanasia |
---|---|---|---|---|---|---|---|
rhMOG1 | 3.3y | F | 657 | 4w | 4w | 8w | 8w |
rhMOG2 | 3.3y | F | 446 | 5w | 4w | 10w | 10w |
WMH1 | 4.5y | M | 401 | 4w | 4w | 4w | 7w |
WMH2 | 2.6y | M | 417 | 16w | 15w | 11w | 28w |
Control1 | 4y | F | 507 | ||||
Control2 | 3.7y | F | 386 |
Abbreviations. rhMOG: recombinant human myelin oligodendrocyte glycoprotein; WMH: white matter homogenate; w: weeks; y: years; F: female; M: male.