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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: J Surg Res. 2015 Nov 5;201(1):226–234. doi: 10.1016/j.jss.2015.10.044

Figure 3. Ghrelin administration significantly stimulates weight gain and reduces postoperative adhesion formation in wild type mice.

Figure 3

The body weight gain in the ghrelin-treated group (n=19) was significantly higher than in the saline-treated group (n= 19). No significant difference in body weight gain between saline (n=10) and ghrelin -treated GHSR KO mice (n=10) (A). Post-surgical adhesions were objectively scored using a scoring system described by Mazuji (Mazuji MK et al, 1964). Ghrelin administration (n=19) reduced significantly post-operative adhesion formations compared to controls (n=19) in wild type mice. No significant difference were detected between saline (n=10) and ghrelin (n=10)-treated GHSR KO mice (B). Data are analyzed by Student’s t-test and One way ANOVA followed by Bonferroni post hoc analysis (*** p-value < 0.001, ** p-value <0.01, * p-value < 0.05).