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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: J Neuroimmune Pharmacol. 2015 Nov 4;11(1):9–25. doi: 10.1007/s11481-015-9637-6

Fig. 2. Analysis of hyperphosphorylated tau (pSer199/202) in hippocampus, four days after intracranial injection of antibodies into one-year old rTg4510 mice.

Fig. 2

The right hemisphere pathology, normalized by the uninjected left hemisphere, showed a marked response to two of the three different antibodies, compared to the anti-GFP control injection. DA 9 treatment yielded a moderate reduction in pSer199/202 staining (p < 0.05), while MC-1 treatment led to an even more dramatic reduction of pSer199/202 (p< 0.01; n = 6 – 8 animals per group)). Statistics were computed using StatView software and ANOVA analysis. Scale bar = 100 μm