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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: J Neuroimmune Pharmacol. 2015 Nov 4;11(1):9–25. doi: 10.1007/s11481-015-9637-6

Fig. 4. Cognitive-behavioral results from rTg4510 mice after receiving 2 weeks of continuous infusion of anti-tau antibodies into the right ventricle.

Fig. 4

Mice that had received two weeks of antibody infusion were subjected to a battery of behavioral testing, with emphasis on cognitive performance. Novel object recognition testing revealed that the IgG1 control antibody (n = 9) did not lead to performance improvement compared to Non Tg mice (n = 8). In contrast, MC-1 treated mice (n = 8) showed cognitive performance levels that were nearly indistinguishable from the Non Tg mice. ANOVA statistical analysis was performed using StatView software