Table 3.
STAIN | Anti-GFP Treatment Mean +/− SEM | MC-1 Treatment Mean +/− SEM | PHF1 Treatment Mean +/− SEM | DA9 Treatment Mean +/− SEM |
---|---|---|---|---|
pSer396 | 1.03 +/− 0.21 | 0.90 +/− 0.156 | 0.75 +/− 0.14 | 1.36 +/− 0.22 |
CD45 | 1.06 +/− 0.13 | 0.96 +/− 0.12 | 1.13 +/− 0.11 | 1.06 +/− 0.10 |
Sub-populations of mice were stained with other phospho-epitopes of tau; here we show an example using pSer396, which did not demonstrate significant reduction in pathology, similar to others tested. Additionally, we examined the microglial marker CD45 to note if antibody treatment had any impact on pro-inflammatory response, which was not reflected here.