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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Biotechnol Adv. 2015 May 27;33(6 0 1):980–991. doi: 10.1016/j.biotechadv.2015.05.004

Fig. 3.

Fig. 3

Oesophagostomum dentatum and pig use non-orthologous enzymes for selected, crucial metabolic reactions. An example of non-orthologous enzyme usage in host and parasite is shown. Ellipses represent metabolites; rectangles represent reaction steps in the pathway, with divisions inside the rectangles representing different KEGG orthology groups of enzymes that catalyze that reaction. Reactions phosphoglycerate mutase (R01518) and glyceraldehyde 3-P dehydrogenase (R01061) are critical glycolysis steps that are catalyzed by enzymes belonging to different KEGG orthology groups in the two organisms, as evident by the different KO identification codes (IDs) in the schematic.