Table 2.
Histopathologic scores in groups.
| Groups | Proximal tubulus | Mononuclear cell infiltration | Capillary vasodilation | Total cell injury score |
|---|---|---|---|---|
| Group I (nondiabetic sham) (n = 7) |
0.14 ± 0.38 0.0 0-1 |
0.29 ± 0.49 0.0 0-1 |
0.29 ± 0.49 0.0 0-1 |
0.71 ± 1.11 0.0 0–3 |
|
| ||||
| Group II (diabetic sham) (n = 6) |
1.33 ± 0.52 1.0 1-2 |
1.33 ± 0.52 1.0 1-2 |
1.17 ± 0.41 1.0 1-2 |
3.83 ± 0.98 3.5 3–5 |
|
| ||||
| Group III (diabetic IR) (n = 6) |
1.83 ± 0.41 2.0 1-2 |
1.66 ± 0.52 2.0 1-2 |
1.5 ± 0.55 1.5 1-2 |
5.0 ± 1.09 5.0 4–6 |
|
| ||||
| Group IV (diabetic IR + LIPC) (n = 6) |
2.33 ± 0.52 2.0 2-3 |
2.17 ± 0.75 2.0 1–3 |
2.17 ± 0.41 2.0 2-3 |
6.67 ± 0.82 6.5 6–8 |
|
| ||||
| p values | ||||
| p 12 | 0.003 | 0.008 | 0.010 | 0.004 |
| p 13 | 0.001 | 0.004 | 0.006 | 0.002 |
| p 14 | 0.001 | 0.003 | 0.001 | 0.002 |
| p 23 | 0.093 | 0.269 | 0.241 | 0.082 |
| p 24 | 0.014 | 0.057 | 0.006 | 0.003 |
| p 34 | 0.092 | 0.206 | 0.043 | 0.020 |
Group I: nondiabetic sham, Group II: diabetic sham, Group III (diabetic IR): renal ischemia/reperfusion injury in diabetic rats group, and Group IV (diabetic IR + LIPC): renal ischemia/reperfusion injury in diabetic rats group and local ischemia preconditioning; Mann-Whitney U test was conducted to compare two independent groups. Values are mean ± 1 SD, median (minimum-maximum).
p 12: comparison of nondiabetic sham and diabetic sham.
p 13: comparison of nondiabetic sham and diabetic IR.
p 14: comparison of nondiabetic sham and diabetic IR + LIPC.
p 23: comparison of diabetic sham and diabetic IR.
p 24: comparison of diabetic sham and diabetic IR + LIPC.
p 34: comparison of diabetic IR and diabetic IR + LIPC.