Table 1.
Sensitive genes from FBA analysis of the complemented network.
Biological processes | Sensitive genes* |
---|---|
Transport, mitochondria | MITC14/MITC18/PTB8/PTB7/PTB1/PTB12/PTB4/PTB2/CRv4_Au5.213.g4507.t1 |
Phenylalanine tyrosine and tryptophan | AST4/HIS5 |
TCA cycle/CO2 fixation | ACH1/IDH3/SDH1/SDH2/OGD1 |
Valine, leucine, and isoleucine degradation | CRv4_Au5.s4.g11844.t1/Crv4_Au5.s12.g3863.t1/CRv4_Au5.s6.g13618.t1/CRv4_Au5.s12.g3863.t1/g1910.t1 |
Pyruvate metabolism; Glyoxylate metabolism | HYDA1/MFDX/HYDA2/PFL1/ACK2/AACK1/ACK1/PAT1/PAT2/CRv4_Au5.s6.g13230.t1/CRv4_Au5.s2.g9723.t1 |
Alanine and aspartate metabolism; glycerine, serine, and threonine | AST3/AST1 |
Carbon fixation | AAT1/AAT2/MME3/MME6/MDH5/MME2 |
Glycolisis, Gluconeogenesis, Valine, Leucine, and isoleucine degradation | DLDH1/PDC2/PDH2/ALSS1/ALSL1/PYK1/PYK5/PHG1/GAP3/GAP1/PGM2/PGM5/PGM1B/PGK1/TPIC/FBA1/FBA2/PGI1/GPM2 |
Transport, extracellular | NAR1.6/NAR1.3/NAR1.4 |
Pentose phosphate pathway | TAL1/TRK1/RPE1/RPI1 |
Glycine, serine, and threonine metabolism | Crv4_Au5.s10.g124.t2/THD1/SHMT3 |
Transport, chloroplast | AOC6/AOC5/AOT7/DAT1/OMT1/AOT5/FBB13/NAR1.5/NAR1.2/NAR1.1/AAA3/AAA1/CRv4_Au5.s14.g5515.t1/CRv4_Au5.s15.g5921.t1/CRv4_Au5.g14736.t1/MOT20/MIP1/MIP2 |
Butanoate metabolism | CRv4_Au5.s7.g14479.t1/CRv4_Au5.s16.g6952.t1 |
Oxidative phosphorylation | NDA3/NUO11/NUO10/NUO13/NUO21/NUO3/NUO5/NUO6/NUO8/NUO9/IPY1/IPY3 |
Propanoate metabolism | PFL1 |
Nitrogen metabolism | CGL77/IBA57/GCST |
Bold type names represent common sensitive genes present in both metabolic reconstructions of Chang et al. (2011) and our present complemented reconstructed network.