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. 2016 Feb 9;10:28. doi: 10.3389/fnins.2016.00028

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Copyright © 2016 Dura-Bernal, Li, Neymotin, Francis, Principe and Lytton.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Raster plot and population peri-event time histogram (PETH) of the original (black), lesioned (red), and repaired (green) motor population. Overlaps of black and green dots or lines indicate activity that has been restored via neural stimulation. Note how before the neurostimulation is delivered, the activity of the lesioned and repaired networks is identical. Two representative examples are shown: 10% cell lesion of left target reaching (left panel), and 10% synaptic lesion of bottom target reaching (right panel). Cells ids correspond to the motor population (256–511). PETH bin size is 20 ms.