Table 3.
Alteration in the response time in mice treated with Oroxylum indicum before subjecting them to tail immersion test.
| Treatment | Dose (mg/kg b.wt.) | Response time in seconds ± SEM | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Assessment time (h) | |||||||||
| 0 | 0.5 | 1 | 2 | 3 | 4 | 5 | 6 | ||
| Control | 0 | 4.30 ± 0.05 | 4.2 ± 0.20 | 4.03 ± 0.12 | 4.6 ± 0.35 | 4.81 ± 0.51 | 4.62 ± 0.42 | 4.31 ± 0.37 | 4.30 ± 0.40 |
|
| |||||||||
| OIE | 300 | 5.67 ± 0.20 | 6.33 ± 0.15∗ | 6.78 ± 0.51∗ | 8.80 ± 0.06∗ | 7.56 ± 0.05∗ | 6.98 ± 0.15∗ | 6.80 ± 0.20∗ | 6.61 ± 0.27∗ |
| (11.64) | (19.57) | (55.20) | (33.33) | (23.10) | (19.92) | (16.57) | |||
| 250 | 4.69 ± 0.50 | 4.72 ± 0.08∗ | 4.97 ± 0.30∗ | 4.78 ± 0.46∗ | 7.14 ± 0.54∗ | 5.65 ± 0.65∗ | 4.90 ± 0.15∗ | 4.80 ± 0.10∗ | |
| (1.91) | (5.97) | (19.18) | (52.23) | (20.46) | (4.47) | (2.35) | |||
|
| |||||||||
| Diclofenac | 20 | 4.29 ± 0.08 | 4.43 ± 0.20∗ | 5.03 ± 0.11∗ | 6.76 ± 0.5∗ | 7.31 ± 0.57∗ | 6.87 ± 0.48∗ | 6.39 ± 0.47∗ | 4.50 ± 0.70∗ |
| (3.26) | (17.29) | (57.57) | (70.39) | (60.13) | (48.95) | (4.89) | |||
Inhibition (%) is shown in brackets.
N = 10.
∗ P < 0.05 when compared to SPS treated control.