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. 2016 Jan 17;17(4):583–592. doi: 10.22074/cellj.2016.3808

Fig.1.

Fig.1

Dysregulation of microRNA expression in β-thalassemia and sickle cell disease.

In this figure the microRNAs involved in β-thalassemia and sickle cell disease has been depicted. According to upor down-regulation of these miRs, the erythrocyte fate is determined. Some of these are erythrocytes specific microRNA as mir-451 with increased expression during the differentiation of this lineage. miR; MicroRNA.